In the luxuriantly forested foothills of the Nilgiris,this 321 sq km sanctuary is part of a much larger reserve (3000 sq km) which includes Bandipur and Wynad in neighbouring Karnataka and Kerala.
The vegetation is quite varied in this region. The hilly terrain of the Western Ghats, clothed in dense mixed and moist deciduous forests, make Mudumalai (the ancient hills) a most attractive wildlife reserve. Bamboos (Bambusa Arundinacea) Natural teak (Tectona Grandis), Anogeissus latifolia, Terminalia, Crenulata/Terminalia Tomontosa, Grewia, and blooming trees like Indian Labumusum, Aredesia, Solanancea are some of the flora.
The fauna include Elephants, Gaur, Banner, Macaque, Common Langur, Tigers, Leopards, Chital, Panther, Sloth Bear, Python, Barking Deer, Four Horned Antelope, Otter, Crocodiles (Mugger), Giant Flying Squirrel, Sambar, Hyena, Wild Dog, Wild Boar, Mouse Deer, Spotted Deer, Jackal, Hare, Porcupine and Mongoose.